Chris Mayne is back.

The 32-year-old veteran makes his return against Brisbane after sitting out the first two rounds of the season as he recovered from a bout of concussion.

After the Magpies captains run on Wednesday, defender Jordan Roughead praised the Lions outfit and won't be taking them lightly on Thursday night.

"We know they're a strong opposition. Obviously, their form last year was fantastic, saw them go deep in finals and their contest and spread in the middle is really good," Roughead said.

"They've got some pretty strong forwards and strong backs, so they're good across the field and we're going to have to bring out best to roll them on Thursday night."

01:54

Our substitute will be out of the four emergencies; Darcy Cameron, Beau Mccreery, Trey Ruscoe and Nathan Murphy. This will be confirmed one hour before the game starts.

Don't miss the action on Channel 7 and Fox Footy from 7.40pm (AEDT).

See below for the full team.

AFL ROUND 3 v BRISBANE
Thursday 1 April
7.40pm (AEDT)
Marvel Stadium
#AFLPiesLions #gopies

IN: Chris Mayne
OUT: Jamie Elliott (injured), Trey Ruscoe (omitted) 

BECOME A MAGPIE MEMBER TODAY! SIGN UP NOW  

COLLINGWOOD V BRISBANE
B Brayden Maynard Jordan Roughead Jack Madgen
HB John Noble Darcy Moore Jeremy Howe
C Jack Crisp Scott Pendlebury Tyler Brown
HF Callum Brown Brody Mihocek Jordan De Goey
F Will Hoskin-Elliott Mason Cox Josh Thomas
R Brodie Grundy Taylor Adams Steele Sidebottom
INT Chris Mayne Isaac Quaynor Josh Daicos
  Brayden Sier    
SUB TBC    
EMERG Darcy Cameron Beau McCreery Nathan Murphy
  Trey Ruscoe